preclinics offers pharmacokinetic studies in small and large laboratory animals.
We will support you individually from your inquiry until the exchange of samples/results. Our experienced team offers you flexible study designs und stands for a prompt execution of your studies.
single-dosing; multiple-dosing, cross-over design
intravenous, intramuscular, subcutanous, intradermal, intraperitoneal, intranasal, per os, intragastrial by gavage, topical
katheter implantation (Vena jugularis, Arteria carotis communis, bile duct); implantation of osmotic pumps
Sampling sites (species dependent)
tail vein, ear vein, jugular vein, vena saphena, vena cephalica, jugular catheter, carotis katheter, retrobulbar (final), heart puncture (final)
whole blood, serum, plasma, urine, faeces, saliva, bile, hair, tissues, organs
All pharmacokinetic studies include:
- planning & communication with customer
- legal administration
- animal husbandry incl. acclimatization of animals
- dosing of compounds
- sample preparation and storage
- transport of samples
- clinical monitoring for side effects during study
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